PL2303 and FT232 are both common USB-to-serial chips, and they have some differences in functionality and performance. The PL2303 is Prolific's product with a lower cost and higher compatibility for general serial communication needs. FT232 is the product of FTDI, which has higher performance and wider application fields, supports more serial port protocols and functions, and is suitable for more complex serial port communication requirements. Therefore, which chip to choose depends on the specific application scenario and requirements.