Yes, the FT232RL chip needs to be driven in a computer or other device to work properly. Drivers can be downloaded and installed through official websites or other trusted resources to communicate the device with the computer. The driver is the bridge between the device and the computer, it is able to ensure that the device is properly communicating with the computer, and provides the required support and features to meet the needs of the user. Therefore, drivers are essential for FT232RL chips and many other devices.