Gene chip, also known as DNA chip, DNA microarray, oligonucleotide array, refers to the use of in-situ synthesis (or microprinting means), tens of thousands of DNA probes solidified on the surface of the support, generate two-dimensional DNA probe array, and then hybridize with the labeled sample. Rapid, parallel and efficient detection or medical diagnosis of biological samples can be achieved by detecting hybridization signals. Because silicon chips are commonly used as solid phase supports and computer chip preparation technology is used in the preparation process, it is called gene chip technology.