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I think it's okay. It just borrows 5V power from a USB port. If the computer is turned off at night, it will not be powered on, and it will be fine....

Hot mouse pad, USB interface forgot to unplug, inserted overnight. What to do?

I think it's okay. It just borrows 5V power from a USB port. If the computer is turned off at night, it will not be powered on, and it will be fine.