Gene chip technology: The microelectronics revolution in Life sciences At the forefront of bioscience, gene chip technology integrates the exquisite technology of microelectronics, laser scanning and molecular biology, and has become a key tool to promote life science research. This revolutionThe technology uses an orderly array of molecules to detect biomolecules in an efficient manner, significantly improving the efficiency of analysis and reagent utilization. Let's delve into the principle, classification and application of this technology.
Also known as "gene microarray", this is a fusion of molecular biology, materials science, genetics, physical chemistry, optics and information topology. Gene chips are not chips in the traditional sense. It's actually a tool for detecting genetic specificity. You can think of it as a PH test strip for genes. To figure it outWhite gene chip, first to understand what is "SOUTHREN hybridization".
Gene chip -- "biological information genie" -- On the role of mathematics and computer in modern life science research The 20th century is the century of physical science, and the 21st century is the century of life science. The rapid development of life science, especially biotechnology, is not only closely related to human health, agricultural development and living environment, but also plays a role in promoting the development of other disciplines, the so-called science of today, the technology of tomorrow, and the production of the day after tomorrow.
Biochips) is a cutting-edge technology developed in the mid-1990s. It uses slide and silicon as the carrier to arrange a large number of biological materials in a high density per unit area, so as to achieve the purpose of simultaneously detecting a variety of diseases or analyzing a variety of biological samples in one test. They are also sometimes referred to as gene chips, DNA chips, or Microarrays. The concept comes from computer chips, which are somewhat similar in appearance.
1, DNA chip is also known as gene chip, DNA is short for deoxyribonucleic acid, the genetic material of human life. Because the DNA molecular chain is based on ATGC (A-T, G-C) as the pairing principle, it uses A kind of called "in-situ combinatorial synthetic chemistry" and micro-electronic chip lithography technology or other methods, a large number of specific sequence of DNA fragments are sequentially solidified on glass or silicon chips, thus forming a DNA chip that stores a large amount of life information. 2. Gene chips, also known as DNA chips, are high-tech products developed in the mid-1990s. The chip is about the size of a fingernail, and its substrate is usually processedBack glass piece. The base surface of each chip can be divided into tens of thousands to millions of cells. In the designated cell, a large number of nucleic acid molecules (also called molecular probes) with a specific function and a length of about 20 base sequences can be fixed.
3, the interpretation of the chip refers to an integrated circuit that contains many gate circuits. Small size, less power consumption, low cost, fast speed, widely used in electronic computing machines, communication equipment, robots or household appliances and other aspects. Definition of the word "core" core "peeled" rush ": a wick (also called" wick "). The center of the core i object75 Chip difference
Power output, function expansion. Power output: The maximum power output of the DNA60 chip is 60 watts, while the maximum power output of the DNA75 chip is 75 watts, which means that the DNA75 chip can provide higher power output, suitable for some users with higher power needs. Function expansion: The DNA75 chip supports more working modes, such as temperature control mode, power mode, voltage mode, etc., while the DNA60 chip only supports basic power mode.
DNA chip, also known as gene chip, DNA is human life genetic materialShort for plasmic deoxyribonucleic acid. Because the DNA molecular chain is based on ATGC (A-T, G-C) as the pairing principle, it uses A kind of called "in-situ combinatorial synthetic chemistry" and micro-electronic chip lithography technology or other methods, a large number of specific sequence of DNA fragments are sequentially solidified on glass or silicon chips, thus forming a DNA chip that stores a large amount of life information.
Comparison between tissue chip and DNA chip and protein chip: Tissue chip and gene chip and protein chip together constitute the biochip series. DNA chips are relatively simple. They're pre-programmed on the chipA nucleotide fragment containing the target gene sequence is printed, and the labeled sample is then hybridized with it.
Gene expression tests can also be used to quantify DNA, which is important for detecting gene copy number and chromosome ploidy. Most electronic products now rely on chips to perform calculations, including in areas such as communications and networking. A chip is an integrated circuit chip manufactured on the surface of a semiconductor chip, which performs operations by controlling and processing circuit signals. The role of the chip enables electronic products to carry out complex operations, improving the speed and efficiency of operations.
[Answer] B. [Answer] B. Analysis: Aluminum is widely used in the aviation field because of its low density. 70% of modern aircraft are made of aluminum and aluminum alloys, so people call aluminum "the flying metal." Because of its wide application in the energy industry, lithium is known as "the energy metal of the 21st century" and "high energy metal". Item B is wrong. So the answer is B.
>> A: The general knowledge of geography. (A) Ocean tides are a natural occurrence in coastal areasImage refers to the periodic rise and fall of sea water under the action of the moon and the sun's tidal forces, and has nothing to do with the Earth's gravity. Item B is correct, 5G is the abbreviation of the fifth generation mobile communication and its technology, is the latest generation of cellular mobile communication technology, and is also an extension after 4G, 3G and 2G systems.
Item A is correct, 5G is short for the fifth generation mobile communication technology, with high speed, low delay, low cost and other characteristics. Item B is correct, semiconductor refers to the normal temperature state, conductive properties between conductors and insulators of materials, in integrated circuits, photovoltaic power generation, LED lighting are widely usedThe application of. Iron is the main material for steelmaking and is the most widely used metal in modern life.
So called X-ray, the scientific community also called it Roentgen ray, Roentgen also because of this discovery won the Nobel Prize, so the B statement is correct. Maxwell is a famous British physicist and mathematician, he established the electromagnetic wave theory of electricity, magnetism and optics unified, so the C statement is correct. In 1957, the Soviet Union launched the first artificial satellite, and "Mars Pathfinder" was launched by the United States in 1996, so the statement D is wrong.CC. Analysis: The so-called "Internet" refers to the diffusion and application process of a set of Internet-based information technologies (including mobile Internet, cloud computing, big data technology, etc.) in various sectors of economic and social life. The essence of "Internet" is the online and digital of traditional industries. The answer to this question is C.
1, gene chip is also known as DNA chip or DNA microarray (DNA microarray).
2, nucleic acid molecular hybridization technology. The essence of gene chip technology is the parallel analysis of biological signals, using the principle of nucleic acid molecular hybridization, through fluorescence labeling technology to detect the compatibility of hybridization, and then through computer analysis and processing can quickly obtain the required information.
3, because the mainstream technology has not yet been formed, there are many forms of biochips, which are divided into matrix materials, including nylon film, glass sheet, plastic, silicone chip, micro magnetic beads, etc.; According to the types of biological signals detected, there are nucleic acids, proteins, biological tissue fragments and even complete living cells; According to the working principle of classification, there are hybrid type, synthetic, connectedGrafting type, affinity recognition type, etc.
4, this revolutionary technology, like the microscopic puzzle of DNA, also known as DNA chips or microarrays, it plays a key role in the field of molecular biology. (One of the core technologies is the clever arrangement of a large number of preset sequence of probe molecules), these probes like precision soldiers, neatly arranged on a special carrier such as silicon, slide or cellulose nitrate film.
5, in the forefront of biological science, gene chip technology integrates the exquisite technology of microelectronics, laser scanning and molecular biology, and becomes the promotion of lifeA key tool for research. This revolutionary technology enables the detection of biomolecules in an efficient manner through an orderly array of molecules, significantly improving analytical efficiency and reagent utilization. Let's delve into the principle, classification and application of this technology.